Once My Best Friend, Now My Worst Enemy

As many of you know, my child is what we call a "MacGyver." He can get out of anything in a matter of seconds. He climbed out of his crib when he was about 18 months and he could get out by the time I turned my back and shut the door to his room. Once the door was shut, I could hear him knocking on the door. What the heck? He's been able to open my mom's doors since he was able to walk and pull the handle (11 months) and he's been able to open the knob doors ever since he was 19 months. Last month he learned how to undo our deadbolts (on both our door and glass door) and now we've reached the limit...he's learned how to do the knob covers!!! He's been in his big boy bed for about 3 months now and we put a knob cover on the inside knob of his room so he couldn't get out or else he'd just escape every time we'd put him down. For the past 3 mornings I have woken up to him standing next to my side of the bed and saying, "Mama wate up." He used to just stand by his door and knock on it until I came to get him. Last night was a huge pain to put him to bed because he kept opening the door and running out. I hate getting frustrated with him and being so stern with him, but it happens. What am I going to do now? Am I going to have to reverse the doorknobs so I can lock him in? Do you have any tricks I could try? I'm going to buy some locks to go on our front and back door sthat go on the top of the door so he can't open them. Help me!